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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: WDR7 All Species: 44.85
Human Site: S1246 Identified Species: 82.22
UniProt: Q9Y4E6 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9Y4E6 NP_056100.2 1490 163810 S1246 I T M G L P L S P A A D S A R
Chimpanzee Pan troglodytes XP_523934 1490 163873 S1246 I T M G L P L S P A A D S A R
Rhesus Macaque Macaca mulatta XP_001084761 1490 163815 S1246 I T M G L P L S P A A D S A R
Dog Lupus familis XP_533395 1491 164172 S1247 I T M G L P L S P A A D S A R
Cat Felis silvestris
Mouse Mus musculus Q920I9 1489 163386 S1245 I T M G L P L S P A A D S A R
Rat Rattus norvegicus Q9ERH3 1488 163172 S1244 I T M G L P L S P A A D S A R
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001510427 1487 163542 S1243 I T M G L P L S P A A D S A R
Chicken Gallus gallus XP_001231557 1487 163610 S1243 I T M G L P L S P A A D S A R
Frog Xenopus laevis NP_001085633 956 105584 S732 G S S D K G G S F L A G K R A
Zebra Danio Brachydanio rerio XP_701317 1059 116678 S835 I S R G G H M S L M L P T F K
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_569960 1525 168458 T1287 L N Y K L P L T P Q A D A C R
Honey Bee Apis mellifera XP_395749 1488 164925 T1248 M T Y G L P L T P Q A D T C R
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_784047 1449 158495 T1210 S A C G L P I T P A A D S C R
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.5 99.2 96.9 N.A. 94.9 94.5 N.A. 93.3 90.4 55.7 57.3 N.A. 41.9 45.5 N.A. 47.2
Protein Similarity: 100 99.7 99.7 98.4 N.A. 97.3 97.1 N.A. 96.4 95.3 60.4 64.3 N.A. 61.6 65.2 N.A. 66.1
P-Site Identity: 100 100 100 100 N.A. 100 100 N.A. 100 100 13.3 20 N.A. 46.6 60 N.A. 60
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. 100 100 20 46.6 N.A. 66.6 80 N.A. 73.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 8 0 0 0 0 0 0 0 70 93 0 8 62 8 % A
% Cys: 0 0 8 0 0 0 0 0 0 0 0 0 0 24 0 % C
% Asp: 0 0 0 8 0 0 0 0 0 0 0 85 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 8 0 0 0 0 8 0 % F
% Gly: 8 0 0 85 8 8 8 0 0 0 0 8 0 0 0 % G
% His: 0 0 0 0 0 8 0 0 0 0 0 0 0 0 0 % H
% Ile: 70 0 0 0 0 0 8 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 8 8 0 0 0 0 0 0 0 8 0 8 % K
% Leu: 8 0 0 0 85 0 77 0 8 8 8 0 0 0 0 % L
% Met: 8 0 62 0 0 0 8 0 0 8 0 0 0 0 0 % M
% Asn: 0 8 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 85 0 0 85 0 0 8 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 16 0 0 0 0 0 % Q
% Arg: 0 0 8 0 0 0 0 0 0 0 0 0 0 8 85 % R
% Ser: 8 16 8 0 0 0 0 77 0 0 0 0 70 0 0 % S
% Thr: 0 70 0 0 0 0 0 24 0 0 0 0 16 0 0 % T
% Val: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 16 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _